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The enzyme transfers -Glu-Cys moieties of glutathione to glutathione or (-Glu-Cys)n-Gly, ultimately producing (-Glu-Cys) n+1 -Gly peptides with n in the range from 2 to 10 (Figure 4)
Given the peptide molecular weight of 5,414.9 Da and 39 amino acid sequence including non-standard residues, mass spectrometry confirmation of the correct molecular species is essential
The best dietary sources of natural folates are leafy greens, beetroot, mushrooms, shellfish, eggs, sprouts, beans and organ meats
Phase Weeks 3+ (standard) Daily dose 100 mg once daily Notes The most common research community target dose
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