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Typical 16-Week Titration Pre-blended CagriSema Titration (mirrors REDEFINE protocol structure) Week 14 Cagrilintide 0.25 mg Semaglutide 0.25 mg Notes Initiation: gastrointestinal tolerability is highest priority

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2, mixed in the same syringe, once a day for 2 days

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From an economic standpoint, obesity is associated with an $1861 annual medical cost per person

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