Halliwell B (1996) Vitamin C: antioxidant or pro-oxidant in vivo
They might have decreased kidney function, drug interactions, and more malabsorption issues
We always run NAD+ slowly
When choosing a supplement, look for clean labels and transparent sourcing to ensure you aren't accidentally introducing a trigger
In tumor cells, MTH1 acts as a protective factor against DNA damage, potentially to avert apoptosis induced by such damage, and may be upregulated in response
In breast cancer cells, caudatin enhanced TRAIL-induced apoptosis by boosting DR5 expression through a CHOP (C/EBP homologous protein)-dependent pathway along with sustained p38 MAPK and JNK signaling (Fei et al., 2019) (Table 1, Row 6)