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References: Delta-sleep-inducing peptide (DSIP): an update PubMed DSIP in insomnia PubMed Delta-sleep-inducing peptide (DSIP): a review PubMed DSIPa tool for investigating the sleep onset mechanism: a review PubMed DSIP in sleep disturbances PubMed The phosphorylated analogue of DSIP enhances slow wave sleep and paradoxical sleep in unrestrained rats PubMed Human plasma DSIP decreases at the initiation of sleep at different circadian times PubMed The effects of delta-sleep-inducing peptide (DSIP) on wakefulness and sleep patterns in the cat PubMed Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions PubMed Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints PubMed A combined effect of fish-originated collagen peptides and caffeine on the cognitive function of sleep-deprived mice PubMed The temporal relation between HGH release and sleep stage changes at nocturnal sleep onset in man PubMed

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doi:10.1016/j.biopha.2024.117202 104

Others are good candidates for a carefully supervised GLP-1 protocol, integrated with peptide therapy and hormone support to protect lean mass and long-term metabolic function