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Compare GLP-1s to metformin instead, and the advantage mostly shrinks
Therefore, we measured the metabolite levels and the regional DA D1R bindings with a specific PET radioligand of 11 C-SCH23390
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and Lindstedt, G
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In addition, we found here that inhibition of either the mitochondrial (IDH2) or cytosolic (IDH1 and ME1) NADPH-producing enzymes diminishes ER stress, and we have found previously that inhibition of the pentose phosphate pathway does likewise (Tyra et al., 2012)
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