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In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (Cuadrado et al., 2019
Glutathione provides a fascinating fail-safe mechanism known as protein S-glutathionylation
Interview dated 10th November 2022
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With heightened interest in antioxidants for immune support, now is the ideal time to direct focus to the worlds most powerful antioxidant, glutathione
