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Side Effects: Long-term use can sometimes cause side effects that outweigh the benefits, such as gastrointestinal discomfort from orlistat or nausea from semaglutide

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doi:10.1124/pr.115.010629

Users must weigh these potential side effects against the benefits of improving glycemic control and managing body weight

Ive spent 20 years trying to sell the benefits of a 5 percent weight loss, said Dr