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Lee SW, Rho JH, Lee SY, Chung WT, Oh YJ, Kim JH, Yoo SH, Kwon WY, Bae JY, Seo SY, Sun H, Kim HY, Yoo YH

When a GLP-1 medication is exposed to high heat or extreme cold, the delicate chemical bonds that hold the peptide together can begin to break down

These compounded preparations are subject to different regulatory standards than FDA-approved manufactured drugs

It is speculated that such bile acid derivatives, and possibly other drugs targeting bile acid activity, may help to better fight gallstone disease (Yu 2016