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And I wanted to get off of methotrexate, the potent medication I was taking for my rheumatoid arthritis

Three systems adjusting simultaneously requires more adaptation time

GLP-1 medications have transformed obesity treatment for many individuals, helping to regulate appetite and support weight loss

PMID 26978405

Tirzepatide is generally prescribed for individuals classified as obese, with a body mass index (BMI) that is 30 or above

Sun L, Zheng ZM, Shao CS, Zhang ZY, Li MW, Wang L, Wang H, Zhao GH, Wang P (2022) Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists