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Certain peptides may stimulate regulatory T cells, reduce inflammatory cytokines, or support tissue regeneration

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Figure 5 3.2.3 Blood cell populations In line with impaired immunoglobulin production, several blood cell defects, including dysregulation of B cell maturation, have been described in various CPs, especially in ICF and Kabuki syndromes (141, 163)

Therefore, CB-839 has been tested in many clinical trials, including colorectal cancer (NCT02861300), triple-negative breast cancer (NCT02071862), renal cell carcinoma (NCT03163667), melanoma (NCT02771626), and others (Table 2)