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In cases of severe deficiency or pernicious anemia, injections may be given daily or weekly initially, followed by maintenance doses every month

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Alternatively, they may be deficient in B12 for other reasons

An endotoxin-free peptide helps ensure that observed experimental outcomes are attributable to the peptide itself rather than unintended immune or inflammatory responses caused by endotoxin contamination

In cases where an allergy is confirmed, there may be a desensitization procedure that involves gradually exposing someone to increasing doses of the allergen under medical supervision

Injections may be especially useful for folks with a documented deficiency or those with a medical condition that makes it more difficult for nutrients to be absorbed in the gut