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The oral formulation (Rybelsus) starts at 3 mg daily, increasing to 7 mg and potentially 14 mg at monthly intervals
Future investigation could determine whether the effects of semaglutide and other GLP-1 receptor agonists on drug self-administration are sex-dependent
When appetite is suppressed, the path of least resistance is to just eat less of everything
Larger and longer studies in broader populations are needed to fully understand the safety and efficacy in people with alcohol use disorder, but these initial findings are promising. In the research, published in the journal JAMA Psychiatry, 48 people with drinking problems were recruited, who had not been actively seeking treatment
Some individuals may experience digestive side effects when starting GLP-1 therapy, including nausea, bloating, early fullness, constipation, or loose stools
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