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BPC-157, short for Body Protection Compound-157, is a synthetic peptide consisting of 15 amino acids derived from a protective protein naturally found in human gastric juice
Lysine 17 (K17) with Glu1.33b: Before branching out into the complex lipidation spacer, the primary amine of the Lys17 residue on the peptide engages in a highly specific salt bridge with the negatively charged glutamic acid located at position 1.33b of the GLP-1 receptor
Abstract Body-protective compound (BPC) 157 demonstrates protective effects against damage to various organs and tissues
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The percentage of patients diagnosed with thyroid cancer was 0.23% in the DPP4i group, 0.17% in the GLP-1RA group, 0.17% in the SGLT2i group, and 0.20% in the SU group
doi: 10.1016/S0140-6736(19)32517-6 Summary Keywords non-alcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, insulin resistance, metabolic syndrome, metabolic disease, fibroblast growth factor 21 Citation Tillman EJ and Rolph T (2020) FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases
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