DPP-4 Inhibitors Mechanism of action Competitive inhibition of dipeptidyl-peptidase 4 slows degradation of endogenous incretins (GLP-1, GIP) Glucose-dependent insulin secretion Post-prandial glucagon release No direct effect on weight or insulin sensitivity Glycaemic efficacy Advantages Weight-neutral useful when metformin + SU cause weight concern Low hypoglycaemia risk (incretin-dependent action) Oral, generally once-daily
This process can aid in weight loss and improve athletic performance, such as increased endurance
J R Soc Med 2015;108:266-79
Medically requires the immediate addition of internal detox therapy (High-Dose Vitamin C / Mild Glutathione IV)
Therefore, if you are experiencing night sweats whilst taking Mounjaro, it is essential to consider alternative explanations and discuss your symptoms with your GP or diabetes specialist nurse to ensure appropriate assessment and management
Since compounded semaglutide doesnt undergo this process, there are risks like dosing errors and counterfeit products, Dr