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This appliance has the advantage that it offers a shorter treatment time than other appliances because it is a fixed appliance that maintains the force during the entire treatment period

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5 Mechanistically, exercise-induced interleukin-6 (IL-6) appears to stimulate GLP-1 secretion from intestinal L-cells and pancreatic -cells in experimental models, which may contribute to improved appetite regulation and insulin secretion during and after exercise

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