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Biochimie 116 , 1723 (2015)
Planchard, D
Levels or activity of DIP-related pathways may be altered during periods of chronic stress, sleep disruption, aging, or neurological imbalance
Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene targeted by every compound in the class), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor linked to glucose homeostasis and GLP-1 secretion) map baseline metabolic biology
Many people assume these symptoms are just part of being on a GLP-1 medication
Some people report lower alcohol consumption and fewer cravings while on tirzepatide
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