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Small air bubbles in a subcutaneous injection aren't dangerous, but removing them ensures accurate dosing

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But we might adjust the schedule for some patients

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(PMC) A separate metabolism-focused paper reviewing human trial history makes a similar point: early signals of weight loss were not consistently reproduced in later studies, particularly when intensive diet/exercise protocols were included

This includes patients with pernicious anemia, a condition where the body cannot absorb B12 from food