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Newborns (especially preterm) lack the ability to metabolize benzyl alcohol, leading to metabolic acidosis, respiratory distress, hypotension and (in reported cases) the often-fatal gasping syndrome. For this reason, only preservative-free sterile water (no benzyl alcohol) is used in pediatric or neonatal care

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Trehalose also functions as a stress-protective molecule involved in maintaining membrane integrity in bacteria, yeasts 53 and insects 54

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Aust Fam Phys 20:12851288 Djupesland PG, Messina JC, Mahmoud RA (2014) The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview