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Animal studies have confirmed that subcutaneous injection in one body area produces collagen synthesis improvements, enhanced angiogenesis, and accelerated wound closure at sites far from the injection point

In severe cases of gout that do not respond to other treatments, surgery may be necessary to remove uric acid crystals from the affected joint

Headache: Occasional headaches have been reported

[Metabolism of paeoniflorin by rat intestinal flora in vitro ]

10.1111/j.1471-4159.2006.03907.x 40 HashimotoS.MatsubaY.TakahashiM.KamanoN.WatamuraN.SasaguriH.et al (2023)

Theyre not drugs, but theyre commonly used as medications