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Unfortunately, these treatments proved to be expensive and have toxic side effects [195]

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Rodic N, Zampella J, Sharma R, Burns KH, Taube JM

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In addition, exendin-4 at 0.1100 nM concentrations for 2496 h increased GLP-1R activation, p53, p21, p38, cAMP, Bax/Bcl-2 ratio, and p38/MAPK activation