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Net lactate accumulation per unit power output was calculated as (LAC 14 -LAC rest )(MP ave ) -1

Although the use of exosomes as a delivery system has its drawback (for example, quickly eliminating by the reticuloendothelial system, lack of efficient encapsulation methods, and potential immune responses), exosomes targeted at tumors may allow systemic administration of miRNA as cancer treatment and are thus worthy of attention

Berberine has the strongest evidence for improving insulin sensitivity and glucose metabolism