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Alternatively, use a 0.3mL low-dead-space syringe for the starting phase, where the finer graduation marks make 5-unit draws more precise

The off-period gives baseline NNMT activity a chance to reset before the next cycle

Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

In this state, its inert and stable