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Effects of terguride, ropinirole, and acetyl-L-carnitine on methamphetamine withdrawal in the rat

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Important: CJC-1295 and Ipamorelin are research/compounded peptides and are not FDA-approved as a weight-loss or anti-aging drug

The rationale is elegant: because GLP-1 receptors are enriched in metabolically active brain regions, using GLP-1 as a delivery vehicle allows estrogen to be directed preferentially toward the central nervous system, potentially enhancing its neuroprotective effects while limiting systemic hormonal exposure

In the mid-2000s, Novo Nordisk had developed a peptide called liraglutide that mimics the gut hormone glucagon-like peptide-1 (GLP-1), leading to antidiabetic effects and weight loss

J Cell Physiol 181: 470-478, 1999