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Simply apply to clean, dry skin

The rationale is elegant: because GLP-1 receptors are enriched in metabolically active brain regions, using GLP-1 as a delivery vehicle allows estrogen to be directed preferentially toward the central nervous system, potentially enhancing its neuroprotective effects while limiting systemic hormonal exposure

Strength Testing as a Lean Mass Proxy Maintaining or increasing strength during Retatrutide treatment suggests successful lean mass preservation

The additional 300 calories per day compared to the 1,400 plan come primarily from increased protein portions and an extra snack or larger carbohydrate servings

It also keeps nerves healthy and aids in DNA creation

DVL3 - dishevelled segment polarity protein 3