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The unfinished puzzle of glutathione physiological functions, an old molecule that still retains many enigmas
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Effects of ligands on gold inhibition of selenium glutathione peroxidase
Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation
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