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Both are NAD+ precursors, meaning that they eventually become NAD+ in cells

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However, if you have diabetes or take other blood-sugar medications, notify your PlexusDx provider about the missed dose so they can monitor your glucose levels

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These mechanisms can influence fatigue in two ways: initial metabolic adjustment during weeks one to four may cause transient tiredness, while sustained metabolic improvement often correlates with increased energy over weeks eight to twelve