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Tier 2: Partial Documentation Acceptable with Caution Criteria partially met: HPLC purity shown but no MS confirmation, in-house lab only, or COA not batch-specific
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Histopathological examination of major organs including liver, kidney, heart, brain, and reproductive tissues shows no treatment-related lesions
This includes if symptoms get better and B12 levels in the blood rise
Vial Integrity: Extreme conditions can affect the glass or plastic of the vial and the rubber stopper, potentially leading to micro-cracks, leaks, or changes in the stoppers sealing ability
