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10 While these effects have been associated with indirect mechanisms such as glucose control and weight loss, scientists have also observed that some of the anti-inflammatory effects begin before a significant reduction in adiposity is achieved

The rumen-protected GABA supplementation increases feed intake and inhibits CCK signaling in growing lambs and cows [155, 156], which may be because GABA is co-expressed and shares the similar signal transduction pathways with CCK [150, 156, 157]

If you have high homocysteine with this genotype, you could focus on increasing dietary folate or supplementing with methylfolate

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