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Efficacy and safety of co-administered once-weekly cagrilintide 2.4 mg with once-weekly semaglutide 2.4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial

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Theoretically, the two compounds target completely different receptor systems (amylin receptors for cagrilintide, GLP-1/GIP/glucagon for retatrutide), which suggests they could work synergistically without receptor overlap

if one or more of these nutrients is lacking, anemia can develop

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