Common side effects are mild and temporary (e.g
We should have the right balance of gut microbes
doi:10.1146/annurev.me.12.020161.001211
When it was first identified as part of a bigger protein in the digestive system, researchers were curious about how it behaved in different tissues, including muscle, tendons, ligaments, nerves, and gut tissue
That question originated in an Australian university laboratory, was carried into a commercial development program with a stabilized analogue, tested in a series of controlled human trials, and ultimately routed away from drug registration and toward a US dietary-ingredient determination
[PMID: 10932736] PubMed record related to this compound for laboratory literature review