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Risks and Unknowns Remaining research gaps include: Long-term systemic administration data Optimal dosing strategies outside dermatology Interaction with copper metabolism disorders Comparative efficacy versus standard wound treatments Most evidence supports local, tissue specific effects rather than systemic transformation

Pregnancy and Breastfeeding Topical use is considered low-risk, but definitive clinical safety data are limited

GHK-Cu + BPC-157 (gut/inflammation stack): BPC-157 focuses on GI repair, tendon healing, and cytoprotection

Case Reports and Conflicts of Interest In the absence of large-scale clinical trials, some practitioners rely on case reports and anecdotal evidence to justify the use of BPC-157

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