When in doubt, keep it that simple
In 2023, Juan P Frias and colleagues, in The Lancet, published the first phase two clinical trial of orforglipron, which investigated the use of a small-molecule oral GLP-1R agonist called orforglipron in type 2 diabetes, which can be taken at any time of the day without restrictions on food and water intake (Frias et al., 2023)
Its not 100% clear that the drugs are associated [with NAION], says Amanda Henderson, MD, chief of the Neuro-ophthalmology Division at the Wilmer Eye Institute and associate professor of medicine at Johns Hopkins School of Medicine
Nissen to help initiate the launch of the SURMOUNT-MMO trial (NCT05556512) in October 2022 (MMO stands for Morbidity and Mortality in Obesity)
Side Effects: Similar to canagliflozin References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)
Yes, and heres exactly how to do it