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There's no evidence that you build tolerance to BPC-157, but cycling off periodically is still considered good practice

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doi: 10.1016/j.ijbiomac.2020.06.274 222 LiX.ZhangJ.LiD.HeC.HeK.XueT.et al

Annu Rev Pharmacol Toxicol 45:5188

With high free fraction and long half-life, it drives strong glucose uptake into cells, lowering blood sugar

Leal FAVD, Gonalves GD, Soncini JGM et al (2022) Exposure to aluminium chloride during the peripuberal period induces prostate damage in male rats