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Although there is currently no direct evidence indicating an association between folate and sex hormone levels, studies have shown that folate can exert a protective effect on sexual organs by alleviating oxidative stress and inflammatory responses, thereby maintaining stable levels of sex hormones in the body [54]

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These discrepancies might be attributed to several factors, including differences in blood sample sources, medication status, disease state, sample processing methods, sample size, and the heterogeneity of OS responses across different stages of schizophrenia