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Korean fermented kimchi, as one of the representative probiotic foods, provides beneficial microorganisms and exerts significant inhibitory effects in the APC/ Min+ polyp model and in colitis-associated cancer, and it has also been clinically proven to significantly suppress the formation or progression of colorectal adenomas 172
Taoufik et al., 2021
However, grapefruit can lead to high drug levels by blocking the CYP3A4 liver protein
It has pharmacological activities such as anti-inflammatory, anti-allergic, anti-asthmatic, and immunomodulatory activities ( in vitro treatment of HEK293T cells and Calu-3 cells with magnolol inhibits ORAI1 (which causes T-lymphocyte and mast cell activation and initiates allergy) and anoctamin 1 (ANO1) (which causes mucin secretion and allergic inflammation) in HEK293T cells and chloride secretion in the Calu-3 cells also reduced IL-2 levels in T-lymphocytes
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