Oral Semaglutide 50 mg Taken Once Per Day in Adults With Overweight or Obesity (OASIS-1): A Randomised, Double-Blind, Placebo-Controlled Phase-3 Trial
Itching, redness, rash or other irritation at site where the GLP-1 medication was injected
Repeating injections in the same location causes lipohypertrophy, thickened fatty tissue that slows medication absorption
Wegovy may delay gastric emptying, which could theoretically affect levothyroxine absorption
Changes take effect at the next billing cycle, and plans can be paused or skipped as needed
Therefore, modeling approaches can be valuable for examining the extent of pharmacokinetic DDIs driven by these mechanisms