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The NAD + decline during normal aging results in oxidative damage, metabolic disorder, circadian rhythm abnormalities, and mitochondrial dysfunction through regulating signaling pathways, such as p53, NF-B, PGC-1 and HIF-1, by sirtuins and PARPs

PloS One (2017) 12:e0179889

First, it's incredibly effective at boosting your body's natural glutathione levelswhich is key when you're trying to fight off free radicals and support healthy cellular function

Ask a clinician first if you have heart, kidney, thyroid, seizure, pregnancy, breastfeeding, or medication concerns

Your provider will design a schedule that accounts for timing and receptor interactions

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