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Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 2021

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Overall, discontinuation due to side effects has been relatively uncommon, suggesting that people have tolerated cagrilintide well

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Over-the-counter options like polyethylene glycol or docusate can help if hydration and fiber are not sufficient

While this mechanism promotes satiety and weight loss, it can also trigger nausea through: Delayed Gastric Emptying : Food remains in the stomach longer, leading to fullness and discomfort