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L-arginine supplements are generally not recommended for people who have: kidney disease low blood pressure (hypotension) guanidinoacetate methyltransferase deficiency, an inherited condition that impacts arginine metabolism L-arginine may also interact with medications like those used to treat high blood pressure

This equalizes pressure and makes it easier to draw medication

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Figure 1 outlines the potential outcomes of familial screening on first-degree relatives (siblings, parents and offspring) of the patient[3]