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Patients with pernicious anemia, intrinsic factor deficiency, or renal impairment require provider oversight

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PMID 1418040

However, the impact of sulforaphane may be broader due to the broader effect of increasing glutathione, including in the hippocampus (region impacted by Alzheimers disease): For their study, published in April 2018 in Molecular Neuropsychiatry, the researchers recruited nine healthy volunteers (four women, five men) to take two capsules with 100 micromoles [17.729mg] daily of sulforaphane in the form of broccoli sprout extract for seven days

This should be compared to a subcutaneous injection in which the needle tip goes into the subcutaneous space rather than the needle