this form of cell death is carried out primarily through the KEAP1/PGAM5/AIFM1 signalling pathway, thereby protecting the organism from ROS-induced damage and inflammation [105]
In CIPN in vivo models induced by cisplatin, postmitotic sensory neurons in the dorsal root ganglion (DRG) are particularly sensitive to cisplatin injury, and axonal damage induced by cisplatin involves multiple events, including ROS generation, suggesting that antioxidants may help reduce the neurotoxicity of cisplatin [124, 125]
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The Journal of the American Medical Association of Neurology reports that higher intake of foods rich in antioxidants, such as vitamin C and vitamin E, may modestly reduce long-term risk of dementia and Alzheimers
Oral glutathione is largely processed through your gut which is why its side effects are digestive
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