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[7] It is well established that low muscle mass and muscle strength are associated with a higher risk of all-cause mortality and disability

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If you are using insulin, your doctor will tell you how to reduce the dose of insulin and will recommend you to monitor your blood sugar more frequently, in order to avoid hyperglycaemia (high blood sugar) and diabetic ketoacidosis (a complication of diabetes that occurs when the body is unable to breakdown glucose because there is not enough insulin)

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In the adrenal cortex, binding of ACTH by melanocortin 2 receptors initiates the production and release of GCs (cortisol in humans, and corticosterone in rodents)