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![glp-1 receptor agonists should be avoided in patients with Weight-Loss Medication Glucagon-like peptide-1 (GLP-1) (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are popular treatments for obesity. The authors discuss the kind of Frontiers | Mechanisms of action](https://www.frontiersin.org/files/Articles/1431292/xml-images/fendo-15-1431292-g001.webp)
![glp-1 receptor agonists should be avoided in patients with Weight-Loss Medication Glucagon-like peptide-1 (GLP-1) (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are popular treatments for obesity. The authors discuss the kind of Frontiers | Mechanisms of action](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41581-025-01036-y/MediaObjects/41581_2025_1036_Fig1_HTML.png)
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![glp-1 receptor agonists should be avoided in patients with Weight-Loss Medication Glucagon-like peptide-1 (GLP-1) (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are popular treatments for obesity. The authors discuss the kind of Frontiers | Mechanisms of action](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs40519-025-01770-z/MediaObjects/40519_2025_1770_Figa_HTML.png)
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