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It is more likely in diabetic patients who are also taking insulin

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This is a sign that the components are falling out of the solution, either from degradation or from temperature-induced changes in solubility

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[PubMed] Hanai T, Shiraki M, Imai K, Suetugu A, Takai K, Shimizu M (2020) Usefulness of carnitine supplementation for the complications of liver cirrhosis