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GIP engagement runs ahead at every dose and reaches roughly 50% occupancy by 15 mg

Bioorg Med Chem (2021) 46

Clinics generally advise against starting treatment for anyone who: Is pregnant Has a personal or family history of thyroid cancer Has a history of multiple endocrine neoplasia (MEN) syndrome BMI and health history serve as a useful starting point for this evaluation, not an absolute cutoff, since metabolism and overall wellness also weigh into a provider's decision

B12 shots are generally safe

Ideal for those grappling with fatigue, stress, or B12 deficiency, this quick injection can help you feel rejuvenated and revitalized

Any sort of GI problem (including hormone imbalances like thyroid problems) may limit absorption