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Some patients could find that they notice weight loss within the first three months of starting semaglutide GLP-1 treatment, although the rate and extent of weight loss can vary based on factors like metabolism, diet, exercise routines, and overall health

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If your refrigerator has cold spots near the freezer compartment, or if you accidentally placed a vial in the freezer and then thawed it, the damage from a single freeze-thaw event can reduce potency by 30-50% or more

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Sweeney et al., 2018)