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Renal tubular effects of prolonged therapy with the GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes mellitus

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Among RNS molecules, peroxynitrite, a product of superoxide anion and nitric oxide, is one of the most prominent one (Ramdial et al., 2017)

Researchers said GLP-1 drugs may curb heart health risks by reducing inflammation, improving blood pressure control, lowering cholesterol and other levels of fat in the blood, and supporting the health of blood vessels

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The SELECT cardiovascular outcomes trial demonstrated that semaglutide reduced the risk of major adverse cardiovascular events (heart attack, stroke, or cardiovascular death) by 20% in patients with obesity and established cardiovascular disease