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While theyre effective in improving blood glucose control and helping patients eat less, GLP-1s are linked with a range of gastrointestinal side effects including constipation, nausea, vomiting and diarrhea, and the significant loss of appetite associated with these drugs can lead to nutrient deficiencies, low energy, decreased muscle mass and a troubling variety of detrimental consequences

If you're new to semaglutide, start with walking or swimming rather than high-impact activities, which demand more cardiac output

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Athletes using Ozempic may find that: Gels and sports drinks become intolerable Pre-run meals sit heavy for too long Hydration becomes more difficult, especially with added carbohydrates Gut distress increases, leading to poor performance and even DNF scenarios Because semaglutide delay gastric emptying, fuel may not be absorbed in time to meet energy demands during training or racing

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