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Additional investigation continues into its role in genomic stability, adaptive cellular response mechanisms, and long-term cellular maintenance processes

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Tesamorelin is the only one of this group with an FDA approval (for HIV-associated lipodystrophy)

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On one hand, FXR protects the liver from bile acid overload by repressing bile salt synthesis through the inhibition of CYP7A1, a process mediated by the induction of small heterodimer partner (SHP)