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This can, however, lead to immunogenicity

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Pregnancy places additional stress on the liver through increased organ burden, altered estrogen metabolism, and immune modulation, which may trigger liver injury or even ALF in some patients with specific comorbidities, such as preeclampsia [4]

If proper titration starting at the lowest dose with gradual 4-week escalation still produces intolerable GI effects, split dosing may allow continued use of the medication rather than abandoning it entirely

For those who see behavioral science as more than just a motivational poster, and for anyone clocking long clinical shifts or parenting on borrowed energy, the system might hold

Liver dysfunction can manifest through: Jaundice : Yellowing of the skin and eyes due to excess bilirubin in the blood